If you have found evidence that is valid, significant and generalized from the study population to your patient, you must decide whether and how to apply the findings to your patient's care.
Applying the best evidence is arguably the Evidenced-Based Practice (EBP) step that requires the most skill. It is at this step that you synthesize the best scientific knowledge with your clinical expertise and the patient's unique values and circumstances to reach a clinical decision:
Before applying evidence from research to your patient, ask yourself:
Guyatt, G. Rennie, D. Meade, MO, Cook, DJ. Users' Guide to Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd Edition 2014.