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Systematic Review Resources

What Is a Systematic Review?

"A review of a clearly formulated question that uses systematic and explicit methods to identify, select, and critically appraise relevant research, and to collect and analyze data from the studies that are included in the review. Statistical methods (meta-analysis) may or may not be used to analyze and summarize the results of the included studies." - from the Cochrane Handbook


In a nutshell, a systematic review is a secondary study from a collection of primary studies (original research) that pertain to a specific research question. Those primary studies have been analyzed, examined, appraised, and evaluated for the highest level of best evidence and quality of methodology, and impartiality.

The process or protocol of doing so is rigorous, strict, and transparent.


Additional Definitions: 

National Health Service


Some Recent Systematic Reviews at NYMC



Da Dong, X., Felsenreich, D. M., Gogna, S., Rojas, A., Zhang, E., Dong, M., et al. (2021). Robotic pancreaticoduodenectomy provides better histopathological outcomes as compared to its open counterpart: A meta-analysis. Scientific Reports, 11(1), 3774-x. doi:10.1038/s41598-021-83391-x [doi]

Daniel Moritz, F., Mahir, G., Joshua, K., Aram, R., Roberto, B., & RoSiX Study Group. (2021). A meta-analysis of DaVinci si versus xi in colorectal surgery. The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS, , e2222. doi:10.1002/rcs.2222 [doi]

Formosa, E. A., Kishimoto, V., Orchanian-Cheff, A., & Hayman, K. (2021). Emergency department interventions for homelessness: A systematic review. Cjem, 23(1), 111-122. doi:10.1007/s43678-020-00008-4 [doi]

Fowler, H., Gachabayov, M., Vimalachandran, D., Clifford, R., Orangio, G. R., & Bergamaschi, R. (2021). Failure of nonoperative management in patients with acute diverticulitis complicated by abscess: A systematic review. International Journal of Colorectal Disease, doi:10.1007/s00384-021-03899-6 [doi]

Kansara, T., Kumar, A., Majmundar, M., & Basman, C. (2021). Mitral regurgitation following PASCAL mitral valve repair system: A single arm meta-analysis. Indian Heart Journal, 73(1), 129-131. doi:S0019-4832(20)30443-0 [pii]

Levy, A. T., Weingarten, S., Ali, A., Quist-Nelson, J., & Berghella, V. (2021). Hands-and-knees posturing and fetal occiput anterior position: A systematic review and meta-analysis. American Journal of Obstetrics & Gynecology MFM, , 100346. doi:S2589-9333(21)00041-0 [pii]

Mahajan, S., Gupta, R., Malik, A. H., Mahajan, P., Aedma, S. K., Aronow, W. S., et al. (2021). Predictors of permanent pacemaker insertion after TAVR: A systematic review and updated meta-analysis. Journal of Cardiovascular Electrophysiology, doi:10.1111/jce.14986 [doi]

Malik, A. H., & Aronow, W. S. (2021). Safety, efficacy, length of stay and patient satisfaction with outpatient management of low-risk pulmonary embolism patients - a meta-analysis. Archives of Medical Science : AMS, 17(1), 245-251. doi:10.5114/aoms/99206 [doi]

Perretta, L., Ouldibbat, L., Hagadorn, J. I., & Brumberg, H. L. (2021). High versus low medium chain triglyceride content of formula for promoting short-term growth of preterm infants. The Cochrane Database of Systematic Reviews, 2, CD002777. doi:10.1002/14651858.CD002777.pub2 [doi]

Sreenivasan, J., Kaul, R., Khan, M. S., Ranka, S., Demmer, R. T., Yuzefpolskaya, M., et al. (2021). Left ventricular assist device implantation in hypertrophic and restrictive cardiomyopathy: A systematic review. ASAIO Journal (American Society for Artificial Internal Organs : 1992), 67(3), 239-244. doi:10.1097/MAT.0000000000001238 [doi]