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Systematic Review Resources

What Is a Systematic Review?

"A review of a clearly formulated question that uses systematic and explicit methods to identify, select, and critically appraise relevant research, and to collect and analyze data from the studies that are included in the review. Statistical methods (meta-analysis) may or may not be used to analyze and summarize the results of the included studies." - from the Cochrane Handbook


In a nutshell, a systematic review is a secondary study from a collection of primary studies (original research) that pertain to a specific research question. Those primary studies have been analyzed, examined, appraised, and evaluated for the highest level of best evidence and quality of methodology, and impartiality.

The process or protocol of doing so is rigorous, strict, and transparent.


Additional Definitions: 

National Health Service


Some Recent Systematic Reviews at NYMC



Bhatt, A. B., Lantin-Hermoso, M. R., Daniels, C. J., Jaquiss, R., Landis, B. J., Marino, B. S., Rathod, R. H., Vincent, R. N., Keller, B. B., & Villafane, J. (2022). Isolated Coarctation of the Aorta: Current Concepts and Perspectives. Front Cardiovasc Med, 9, 817866.

Cheppalli, N. S., Purudappa, P. P., Metikala, S., Reddy, K. I., Singla, A., Patel, H. A., & Kamineni, S. (2022). Superior Capsular Reconstruction Using the Biceps Tendon in the Treatment of Irreparable Massive Rotator Cuff Tears Improves Patient-Reported Outcome Scores: A Systematic Review. Arthrosc Sports Med Rehabil, 4(3), e1235-e1243.

Elfil, M., Bahbah, E. I., Bayoumi, A., Aladawi, M., Eldokmak, M., Salem, M. M., Aboutaleb, P. E., Villafuerte-Trisolini, B., Al-Mufti, F., Ortega-Gutierrez, S., & A Gonzalez-Castellon, M. (2022). Repeated mechanical thrombectomy for recurrent large vessel occlusion: A systematic review and meta-analysis. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 15910199221134307. Advance online publication.

Gupta, R., Behnoush, A. H., Egeler, D., & Aronow, W. S. (2022). Effect of Acetaminophen on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Eur J Prev Cardiol.

Hirani, R., Harutyunyan, A., Phillips, J. L., Choudhury, M., & Drangsholt, S. (2022). Interventions to Reduce Opioid Prescriptions Following Urological Surgery: A Systematic Review and Meta-Analysis. Letter. J Urol, 101097ju0000000000002943.

Isath, A., Elson, D., Kayani, W., Wang, Z., Sharma, S., Naidu, S. S., Jneid, H., & Krittanawong, C. (2022). A meta-analysis of traditional radial access and distal radial access in transradial access for percutaneous coronary procedures. Cardiovascular revascularization medicine : including molecular interventions, S1553-8389(22)00774-6. Advance online publication.

Isath, A., Virani, S. S., Wang, Z., Lavie, C. J., Naidu, S. S., Messerli, F. H., & Krittanawong, C. (2022). Meta-analysis of Per-Day Step Count and All-Cause Mortality. Am J Cardiol, 180, 166-168.

Naftchi, A. F., Vazquez, S., Spirollari, E., Carpenter, A. B., Ng, C., Zeller, S., Feldstein, E., Rawanduzy, C., Das, A., Gabriele, C., Gandhi, R., Stein, A., Frid, I., Dominguez, J. F., Hanft, S. J., Houten, J. K., & Kinon, M. D. (2022). Adult Trauma Patients With Thoracolumbar Injury Classification and Severity Score of 4: A Systematic Review. Clin Spine Surg.

Ng, C., Feldstein, E., Spirollari, E., Vazquez, S., Naftchi, A., Graifman, G., Das, A., Rawanduzy, C., Gabriele, C., Gandhi, R., Zeller, S., Dominguez, J. F., Krystal, J. D., Houten, J. K., & Kinon, M. D. (2022). Management and outcomes of adult traumatic cervical spondyloptosis: A case report and systematic review. J Clin Neurosci, 103, 34-40.

Scudder, A., Rosin, R., Baltich Nelson, B., Boudreaux, E. D., & Larkin, C. (2022). Suicide Screening Tools for Pediatric Emergency Department Patients: A Systematic Review. Front Psychiatry, 13, 916731.

Vazquez, S., Spirollari, E., Ng, C., Naftchi, A. F., Das, A., Carpenter, A., Rawanduzy, C., Garell, P., Rosberger, H., Gandhi, R., Feldstein, E., Shah, S., Dominguez, J. F., Hanft, S., Houten, J. K., & Kinon, M. D. (2022). Classifications and level of evidence trends from the most influential literature on thoracolumbar burst fractures: A bibliometric analysis. N Am Spine Soc J, 10, 100125.

Yang, Y. C., Shetty, S., Koranne, K., Malik, A., & Giudici, M. (2022). A Systematic Review and Single-center Experience of Azygos Vein Defibrillator Lead Insertion. J Innov Card Rhythm Manag, 13(5), 4987-4993.